The Metabolism and Dosage for Viagra
Chemistry of Viagra
The chemistry of Viagra drug
reveals that it is readily absorbed in the human
blood stream, with the maximum time observed for
concentration ranging anywhere between 30 minutes
to 120 minutes from oral dosage.
Further information also reveals that Viagra
is approximately 40 percent bio available, and
has a high protein content of 96 percent.
It is thus advised that Viagra intake must
be accompanied with a rich calorie diet containing
high fat and protein contents. Viagra when taken
with a low fat meal has shown a reduced absorption
rate.
Best Way To Use Viagra
As for the metabolism rate, the half
life and excretion rate from the use of Viagra,
studies to this respect have found that metabolization
activity for Viagra generally takes place through
an enzyme known as CYP3A4 and to a lesser extent
through another enzyme CYPC229 respectively.
Once taken the Viagra breaks down and is excreted
in the feces (80 percent), and through the urine
approximately 13 percent. As for the known half-life
of Viagra, this has been found to be approximately
4 hours.
Another important aspect on the
intake and use of Viagra is that individuals
on medications for either kidney problems, liver
problems or even undergoing a dialysis for kidney,
the dosage for Viagra should be strictly followed
under the specific instructions of the consulting
physician, as these conditions are more than
likely to be affected from the use
of Viagra.
Viagra Dosage
The dosage for Viagra,
like any drug, must also be seriously taken
into account, as the dosage may be different
for each individual, which may vary according
to the unique health status, as well as the
response of the individual's various organs
to the intake of Viagra.
The generally prescribed dosage for Viagra is 50mg taken about 1 hour prior to anticipated
sexual activity. The labeling of the Viagra
however states that Viagra can be taken anytime
from one half hour to 4 hours prior to sexual
activity. |
